Gamma-Amino-Butyric Acid – GABA has been said by many as being the holy grail of supplements for promoting relaxation and reducing anxiety.
GABA is the ‘downer’ in the world of neurotransmitters, counter-balanced by Glutamate—and all the processes involved.
Many other Nootropics on this list, especially the Racetam family, are thought to act by antagonizing GABA-related receptor sites within the brain, indicating the body’s ability to deeply utilize this Nootropic compound. In addition to it’s neurological benefits, GABA is also taken by many as a way to naturally ‘boost’ Growth Hormone levels. GABA has been shown in clinical trials to increase serum Growth Hormone levels by up to 400%, reaching peak at around 1 hour after ingestion. GABA unfortunately shows great difficulty in it’s ability to cross the blood-brain barrier, making effective dosages somewhat larger compared to other Nootropics on this list. For example, many GABA supplements list a single dosage as being 750mg or more.