Cannabidiol – What is it?

There is a thrust for knowledge withing the emergence of extracting CBD and the other Cannabinoids from Hemp plants due its natural element of CBD and lack of THC (though done carefully). Mike Membrino, of Neuro-Endoceuticals asserts that Cannabidiol is one of the most exciting cannabinoids – naturally occurring compound found in Hemp plants – that we are aware of today. Also known as CBD, cannabidiol is transforming from a little-known molecule, to a potential breakthrough nutritional component for treatment of a many disorders under the over-sight of the FDA in clinical trials. This notion is currently preliminary and in the infancy stages of being supported by scientific researchers who are recognizing that taking CBD can be an important option for various neurological illnesses.

Cannabidiol (CBD) is one of the main cannabinoids present in the naturally growing populations and in the industrially cultivated varieties of Hemp Extract. The chemical formula and structure of the CBD element is presented as:


The CBD formula is = C21H30O2

According to Borges et al. (2013), CBD is associated with treatment of pain for patients with multiple sclerosis. Contemporary research has discovered that that CBD possesses the following medical properties as presented by Mike Membrino, President of Neuro-Endoceuticals.

Medical Properties of CBD Effects
Anti-oxidant Possibly beneficial in treating neurodegenerative disorders
Anxiolytic/anti-depressant Possibly improves anxiety and depression
Antiemetic Possibily Improves vomiting and nausea
Anticonvulsant Possibily prevents seizures activities
Anti-inflammatory Possibily combats inflammatory disorders
Antipsychotic Possibily combats psychotic disorders
Anti-tumoral/Anti-Cancer Possibily fights tumor cells and cancer cells


Cannabidiol (CBD) is found throughout the seeds, stalk and flowers of hemp plants including hemp and hemp extract. Unlike many of the 85+ cannabinoids that we are aware of, cannabidiol occurs naturally in significant quantities in hemp, which makes it the second most abundant cannabinoid in the Hemp plant. As a presented by Mike Membrino, CBD tends to interact with our naturally occurring system and does not have any negative effects like THC that is psychotropically active. In effect, this characteristic makes CBD safer, less controversial alternative, and offers important health benefits.

Just taking CBD is not the answer. It has to be formulated properly with a bio-availability in mind. The delivery is just as important as the product itself. Our CBD is extremely effective since its being delivered to the blood stream.

It’s all in BIOAVALABILITY. Per Mike Membrino, the way to understand this properly is the Human body allows some molecules and substances to enter the blood stream more effectively than others based on certain properties of those respective molecules. Our CBD undergoes ONE extra step of proprietary refining prior to leaving our facilities in order to ensure that we have the BEST CBD in the world. Additionally, our CBD may help with benefiting pain reduction, management of inflammation, and sleeping.

Bioavailability – Wikipedia

In pharmacology, bioavailability (BA) is a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. By definition, when a medication is administered intravenously, its bioavailability is 100%. Therefore, with the existing medical hemp market, our CBD have wide arrays of products that can be consumed by various means of administration.

On the other hand, our CBD is characterized by the route of administration that makes it extremely significant to govern the uptake, distribution, and ignition of the body’s own endocannabinoid system. Due to the fact that not all CBD are consumed orally, our CBD have wide arrays in which it can be administered including for oral CBD, oral mucosal CBD through mouth, intranasal, and absorption through the lungs. Soon we will add transdermal as an option.

Finally, Membrino notes that our understanding of CBD hemp oil has expanded and is more interesting in the contemporary medical possibilities of all routes of administartion. In this case, our CBD can be found in liquid and sold form:

  • Capsules
  • Inhalers
  • Syringes
  • Edibles
  • Tinctures
  • Patches (coming soon)

Why use Cannabidiol (CBD) oil Supplements

Various scientific and clinical studies indicate that CBD could be effective in easing symptoms of a wide range of difficult-to-control conditions, including: rheumatoid arthritis, diabetes, alcoholism, PTSD, epilepsy, antibiotic-resistant infections and neurological disorders. Mike Membrino notes that CBD has demonstrated neuroprotective effects, and its anti-cancer potential is currently being explored at several academic research centers in the U.S. and other countries.

On the other hand, studies have shown that cannabidiol is not psychoactive as compared to THC, which is a well-known high inducing molecule found in a cousin plant known as Marijuana. CBD has no euphoria or sedation since it has no THC. This applies to both humans and animals. Similarly, as argued by Mike Membrino, effects of CBD – rich hemp makes it an appealing treatment option for individuals seeking anti-inflammatory, anxiety and other devastating neurodegenerative diseases.

Separately, CBD has been identified to interact with the body through the endogenous endocannabinnoid system.  In such cases, the ECS has been associated with the regulation of the body’s homestasis or the general state of the balance. Including several nervous functions such as mood, appetite, sleep, hormone regulation, and immune response.

In short, CBD interacts with receptors in the nervous system. Its ability to possibly reduce pain, inflammation, anxiety, and depression. Additionally, cannabidiol (CBD) has been shown by the NIH to have significant antioxidant and neuroprotective properties, suggesting that it could be a potential treatment for neurological disorders as presented in the above table. Additionally, recent studies with synthetic cannabinoids indicate that the activation of CB1 receptors can facilitate neurogenesis including

  • The activation of the TRPV1receptor also known as vanilloid. The receptor controls pain and inflammation sensory organs in the body.
  • Activation of GPR55 receptor also known as a blockade. The receptor controls the sensory organs that fight pain in the body.
  • Finally, it activates the serotonin receptor that helps control stress, anxiety, and mood in the body.

While cannabidiol is not yet FDA approved for any condition, many studies have shown promising results for a variety of indications. Additionally, through anecdotal evidence, many people have used CBD products on their own in an effort to treat various medical issues.


Where is CBD found or where does CBD hemp oil Originate?

Cannabidiol is produced in 2 ways:

  1. Naturally, in the hemp plant. Cannabidiol can be found in both hemp and marijuana varieties of cannabis. The main functional difference between hemp and marijuana is the level of THC. Marijuana is grown specifically to contain significant levels of THC – usually for recreational and recently medicinal use, while hemp has only little (<0.3% THC)  or no amounts of THC. CBD found naturally in hemp is also legal on a state level in the United States (like all other hemp products), while CBD from marijuana is federally illegal in the United States, state-by-state legalization is occurring rapidly.
  2. Cannabidiol can also be produced synthetically in a laboratory.

Consequently, growing of hemp for commercial purposes was previously prohibited in the United States, through existing growing domestic demand, it is now legal to grow in a few select states. Importing is still permissible.

Cannabidiol Products and what makes the CBD oil Unique

With the growth in demand for medical marijuana for health reasons, and the legalization movement lagging behind, millions of people are looking for alternative sources of cannabidiol. Because CBD is also a natural ingredient found in hemp, which is legal, the popularity of CBD hemp oil supplements has skyrocketed.

CBD hemp oil products have already been available on the mainstream market for several years now. These include nutritional supplements like daily capsules and drops, gummies, and high concentration extracts. Moreover, CBD hemp oil is a rich nutritional supplement, containing several vitamins and minerals and other healthy constituents. Additionally, CBD is being used to enhance many skin and beauty products, including everything from shampoos to skin creams.

In other words, there exists thousands of unique products of CBD hemp oil supplements. Besides, using the uniquely potent plants, extracting Hemp oil is significant in the sense that it contains higher percentage of CBD together with other essential vitamins, fatty acids, terpenes, flavonoids, and other non-psychoactive cannabinoids.


How is CBD Hemp Oil Used to Create CBD Products?

After the Hemp plants have been harvested, they go through a specialized solvent-free extraction to yield the CBD hemp oil. The pure extract will then be tested for effective (percentage of CBD and other cannabinoids) and safety (lead, etc).

Finally, as mentioned by Mike Membrino, various bodies follow proper safety protocol to double check for degradation, damage, or contamination in our oil, ensuring one receives only safe, reliable CBD hemp oil products locally grown in the USA.

Our formulators will, therefore, combine the CBD oil with other ingredients to make extensive line-ups for various brands. Then as presented by Mike Membrino, our final CBD hemp oil products are tested for a final time after manufacturing to once again ensure the safety, quality, and cannabinoid content of our products before they are shipped directly to our customers’ doors.

Types of CBD hemp oil products available

Neuro-Endoceuticals offers a variety of CBD hemp oils in various forms. Our CBD can be found in liquid and sold form including Capsules, Applicators, Gummies, and Tinctures.

Pure CBD oils

It the most common potent natural CBD oil available. It is naturally extracted from the hemp plant, tested for use and safety then packaged without additional additives. The product contains a pure and high concentration CBD – generally from 80 to 86%.

CBD tinctures or Liquids

Most of the CBD hemp oil is in liquid form. They are made through mixing of the pure hemp CBD oil into a natural oil base; typically MCT Oil is used. Our products come with great flavors, making them enjoyable to all people.

On the other hand, for those concerned about taste, hemp CBD oil tinctures are a pleasant and convenient way to get your cannabidiol oil nutritional supplement. Tinctures feature sweetened and flavored CBD liquid designed to give you all the natural benefits of cannabidiol while tasting great.

CBD capsules

Due the fact that CBD is associated with vitamin and other important elements, most people like it as CBD oil capsules that everyone can consume in a daily routine.

Additionally, CBD hemp oil capsules offer an incredibly convenient way to get your daily intake of cannabidiol. For those always on the move, CBD hemp oil capsules offer our high-quality cannabidiol hemp oil in a handy, easy-to-swallow pill.

CBD oil topical, body, and skin care

CBD oil can also be infused into topical and body care products that allow the skin of your body to absorb the cannabidiol oil in the body for its natural benefits. Mike Membrino, argues that Pure CBD hemp oil is naturally an incredible source of vitamins, omega fatty acids, vitamins, terpenes, and chlorophyll, making it a valuable ingredient for radiant and smooth skin.

In conclusion, Mike Membrino, President of Neuro-Endoceuticals notes that CBD oil products hold many benefits as far as positive side effects are concerned. The following are product advantages:

  • CBD can possibly aid to a quick recovery for the body in cases of intense training averting injuries.
  • CBD can possibly help reduce inflammation.
  • CBD can possibly help muscles recover after intense stretch outs.
  • CBD can possibly contribute to improving sleep as the body recuperates quickly during sleep.
  • CBD can possibly help promote one’s appetite. A good feeding habit is indirectly associated with healthy bodies and quick recovery from injuries and ailments.

How to get our CBD oil products

Due to the fact that CBD is derived from a natural plant and 100% legal in all 50 states to use as a dietary supplement throughout. Please click on the products page to purchase CBD.

Please note that this product has not been evaluated by the FDA. CBD is not intended to diagnose, treat, cure, or prevent any disease.


Borges et al. (2013). Understanding the Molecular aspect of  THC and CBD anti-oxidants. Journal of Molecules